iPSC morphology

What is HipSci?

HipSci brings together diverse constituents in genomics, proteomics, cell biology and clinical genetics to create a UK national iPS cell resource and use it to carry out cellular genetic studies.

Between 2013 and 2017 we aim to generate over 500 iPS cell lines from healthy volunteers and several hundred lines from individuals with genetic disease. We are then using these cell lines to discover how genomic variation impacts on cellular phenotype and identify new disease mechanisms.

Strong links with NHS investigators ensure that studies on the disease-associated cell lines will be linked to extensive clinical information. Further key features of the project are an open access model of data sharing; engagement of the wider clinical genetics community in selecting patient samples; and provision of dedicated laboratory space for collaborative cell phenotyping and differentiation.

Cell lines and data browser