HipSci Rare Disease – Expressions of Interest

April 28, 2015

We are looking to hear from clinicians (or scientist with access to relevant patient cases) working with patients with inherited genetic diseases, where a collection of disease causing mutations has already been identified, and the group would be interested in having iPS lines generated from some of your patients that you would use in further studies.

Please note that at this stage this is only an Expression of Interest and not a final call for proposals. The results will allow us to plan the use our remaining resources most efficiently.

Please contact us if you have a group of (between 10 and 50) patients with related phenotypes where you would be able to provide us with patient material (either fibroblasts or a skin biopsy).

Please see the HipSci Rare Disease Expression of interest page for more information. The details can also be found in the Expression of Interest PDF. The Expression of Interest should be submitted to hipsci-proposal@ebi.ac.uk before 3rd July 2015.

HipSci calls for Rare Disease case proposals

March 20, 2014

We are seeking clinicians (or scientists with access to relevant patient cases) to provide samples from patients with inherited genetic diseases for the disease component of the HipSci project. We request that samples are provided in groups of between 10 and 50 with related phenotypes, and that all samples already have the genetic defect identified (the aim is to support gene analysis rather than gene discovery), with typically multiple cases with defects in the same gene. We encourage clinicians/scientists with only small numbers of samples to form larger groups with others who can contribute similar cases.

If you wish to submit a proposal or have any questions please email hipsci-proposal@ebi.ac.uk Full Details can be found on the iPS cells for Rare disease cases: call for proposals page and in the Proposal PDF

Wellcome Trust and MRC invest £13m to create a new national stem cell resource

November 06, 2012

The Wellcome Trust and Medical Research Council (MRC) today announced a £12.75 million initiative to create a catalogue of high-quality adult stem cells, so-called induced pluripotent stem cells (iPS cells). The initiative will provide a knowledge-base to underpin the use of such cells in studying the effects of our genes on health and disease and lay the foundations to create a new iPS cell bank, providing a world-class resource for UK researchers.