HipSci's rich data

As IPSC lines are increasingly being used as patient-specific disease models, it is crucial to understand the sources of biological variability and heterogeneity in these lines.

Each line generated by HipSci is extensively characterised, with all genetic and phenotypic data freely available for use by the wider research community.

  • Systematic characterisation of hundreds of IPSC lines
  • Extensive genomics, epigenomics, transcriptomics, proteomics, and cellular phenotyping
  • Meta data: donor demographics and cell line derivation methods

A key feature of HipSci’s experimental design is the derivation and characterisation of multiple IPSC lines for each individual. This enables us to quantify the fraction of IPSC cellular variation attributable to donor effects, and to map common genetic variants that affect variability in gene expression between IPSC lines.

Use the links at the top of this page to find out more about HipSci’s data sets and how to access the data.

To start exploring HipSci’s data sets, take a look at the cell lines and data browser

mesoderm differentiation

Cell lines and data browser