This page describes the classification of any HipSci data as:

The following statements are guidelines only. We have policy documents describing how to manage these data types. For general queries please contact hipsci-dcc@ebi.ac.uk for information. For any queries relating to managed access data please contact the HipSci Data Access Administrator wtsidata1@sanger.ac.uk for information.

Individually unique data

Individually unique data are uniquely associated to the cell line’s donor. In particular, data comprising genetic information are classed as individually unique.

Individually unique data can be subject to managed-access restrictions, depending on the consent agreement signed by the sample donor.

Examples of individually unique data are:

  • Genotypes called from genotyping array or exome-seq
  • Sequencing data from exome-seq or RNA-seq

Non-unique data

Non-unique data are not uniquely linkable to the sample donor. All of HipSci’s non-unique data can be distributed openly; they are not subject to managed-access restrictions.

Examples of non-unique data are:

  • Transcript expression quantifications from RNA-seq
  • Proteomics mass spectrometry
  • Cellular phenotyping measurements

Managed access data

The consent agreement of some HipSci donors authorises release of individually unique data only for specific research use to bona fide researchers. ‘Managed access data’ refers to individually unique data from these donors.

Managed access data are store in the EGA archive. For access to these data, researchers must read the Data Access Agreement document (pdf and register for access via WTSI’s Electronic Data Access Mechanism.

Open access data

The consent agreement of some HipSci donors authorises release of individually unique data to all parties, with no requirement to satisfy any data access restrictions.

‘Open access data’ refers to:

  1. Non-unique data from any donor
  2. Individually unique data from donors who have consented to unrestricted data release.

Chromosome Y

Individually unique data (i.e. genotypes) from the male chromosome Y are classed as managed access data for all HipSci donors. This includes donors whose consent agreement allows the free distribution of genotype data from other chromosomes.

Y chromosome data have been stripped from any file containing genetic data in any open access data archives.

Access status in the data browser

Cells lines in the HipSci data browser are marked with their access status. Cell lines can be filtered by access status using the filter options.