To help clinicians engage with open access initiatives like HipSci, we have provided exemplar documents used in this project to provide guidance on what needs to included in the PILs and consent forms, as well as the terms of use found in our end user MTAs for lines deposited at ECACC.

Model ethics #1

The Participant Information Leaflet and the Consent Form are exemplars which cannot be used for enrolment of cases. These documents were generated by the NIHR BioResource and members of the HipSci consortium membership committee. The study was approved by: NRES Committee East of England - Cambridge Central, Study title: Generation of Induced Pluripotent Stem (iPS) Cells and Rare Diseases. REC Ref: 15/EE/0049

Model ethics #2

The following documents have been provided by NIHR Rare Diseases Translational Research Collaboration and the NIHR Great Ormond Street Hospital Biomedical Research Centre. This study was approved by NRES Committee London-Bloomsbury, Study title: Molecular Genetics of Human Birth Defects – mapping and gene identification. REC Ref: 08/H0713/82

ECACC material transfer agreements

The documents attached below are the MTAs that end users must agree to when obtaining cells from ECACC (European Collection of Authenticated Cell Cultures). The terms of use in these documents may be helpful in what text can or cannot be included in your ethics applications